Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial
Background ADVISE (ADaptiVe biomarker trial that InformS Evolution of therapy) (NCT03335540) was a biomarker-adapted feasibility clinical trial of immunohistochemistry (IHC) to inform combination immuno-oncology (I-O) treatment.Methods To inform I-O combination selection, messenger RNA expression an...
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| Main Authors: | Akshita Gupta, Riyue Bao, F Stephen Hodi, Jaclyn Neely, Jason J Luke, Ashish Massey, Santanu Dutta, Janis Taube, George Lee, Katherine Bever, Peter Szabo, David Yao, Rachel Tam, Tim Reilly |
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| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2025-05-01
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| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/13/5/e011170.full |
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