Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial

Background ADVISE (ADaptiVe biomarker trial that InformS Evolution of therapy) (NCT03335540) was a biomarker-adapted feasibility clinical trial of immunohistochemistry (IHC) to inform combination immuno-oncology (I-O) treatment.Methods To inform I-O combination selection, messenger RNA expression an...

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Bibliographic Details
Main Authors: Akshita Gupta, Riyue Bao, F Stephen Hodi, Jaclyn Neely, Jason J Luke, Ashish Massey, Santanu Dutta, Janis Taube, George Lee, Katherine Bever, Peter Szabo, David Yao, Rachel Tam, Tim Reilly
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/5/e011170.full
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