New insights into markers for distinguishing neuroendocrine prostate cancer: evidence from single-cell analysis

New insights into markers for distinguishing neuroendocrine prostate cancer: evidence from single-cell analysis

BackgroundNeuroendocrine prostate cancer (NEPC) is a highly aggressive malignancy with few effective treatment options. The identification of reliable biomarkers for NEPC is essential for early detection and intervention.MethodsWe combined single-cell and bulk transcriptome analysis to identify nove...

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Bibliographic Details
Main Authors: Hailang Luo, Boyang Li, Meng Zhang, Hongqun Wang, Zongyao Hao, Qintao Ge, Chaozhao Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
neuroendocrine prostate cancer (NEPC)
single cell analysis
biomarker
WDFY4
ASCL1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551815/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551815/full

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