Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing.

Massively parallel pyrosequencing of hypervariable regions from small subunit ribosomal RNA (SSU rRNA) genes can sample a microbial community two or three orders of magnitude more deeply per dollar and per hour than capillary sequencing of full-length SSU rRNA. As with full-length rRNA surveys, each...

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Bibliographic Details
Main Authors: Susan M Huse, Les Dethlefsen, Julie A Huber, David Mark Welch, David A Relman, Mitchell L Sogin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000255&type=printable
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