Conditioned medium from painful non-NF2 schwannomatosis tumors increases pain behaviors in mice

Abstract The majority of non-NF2 schwannomatosis (non-NF2 SWN) patients experience debilitating pain. Yet, it is not known why only some schwannomas cause pain or whether mutations in SWN-related genes, (SMARCB1 or LZTR1) differentially influence pain signaling pathways. Here, we established cell li...

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Bibliographic Details
Main Authors: Randy Rubright, Michael J. Caterina, Allan Belzberg, Kimberly Laskie Ostrow
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-99820-0
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