Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.

Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.

<h4>Background</h4>Secretory phospholipase A2 group IIA (sPLA2-IIA) has been identified as a biomarker of atherosclerosis in observational and animal studies. The protein is encoded by the PLA2G2A gene and the aim of this study was to test the functionality of two PLA2G2A non-coding SNPs...

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Main Authors: Holly J Exeter, Lasse Folkersen, Jutta Palmen, Anders Franco-Cereceda, Jackie A Cooper, Anastasia Z Kalea, Ferdinand Van't Hooft, Per Eriksson, Steve E Humphries, Philippa J Talmud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0041139&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0041139&type=printable

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