Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson’s disease model

Abstract Background Parkinson’s disease (PD) is characterized by dopaminergic neuron loss, neuroinflammation, and motor dysfunction. PD is a multifactorial disease, with neuroinflammation driven by NLRP3 inflammasome activation representing an important component of its pathological progression. The...

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Main Authors: Hye-Sun Lim, Jinyoung Park, Eunjeong Kim, Wonhwa Lee, Hwi-Yeol Yun, Seung Hoon Lee, Gunhyuk Park
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Neuroinflammation
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Online Access:https://doi.org/10.1186/s12974-025-03461-z
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