Potential biomarkers of primary resistance to first- and second-generation EGFR-TKIs in non-small-cell lung cancer: a real-world study

Potential biomarkers of primary resistance to first- and second-generation EGFR-TKIs in non-small-cell lung cancer: a real-world study

Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) significantly improve the prognosis of EGFR-sensitive mutant non-small-cell lung cancer (NSCLC). However, the mechanisms underlying primary resistance to EGFR-TKIs remain unclear. Objective: This study aimed to explo...

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Main Authors: Jingyi Wang, Bolin Chen, Xingxiang Pu, Jia Li, Yan Xu, Li Xu, Fang Xu, Kang Li, Yi Kong, Liyu Liu, Qianzhi Wang, Lin Wu
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359251336632
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https://doi.org/10.1177/17588359251336632

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