A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirus.

The pathogenesis of persistent viral infections depends critically on long-term viral loads. Yet what determines these loads is largely unknown. Here, we show that a single CD8+ T cell epitope sets the long-term latent load of a lymphotropic gamma-herpesvirus, Murid herpesvirus-4 (MuHV-4). The MuHV-...

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Bibliographic Details
Main Authors: Sofia Marques, Marta Alenquer, Philip G Stevenson, J Pedro Simas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000177&type=printable
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