Early initiation of SGLT2 inhibitors in acute myocardial infarction and cardiovascular outcomes, an updated systematic review and meta-analysis

Abstract Background Sodium-glucose cotransporter-2 (SGLT2) inhibitors increase survival rate in heart failure, but early initiation of these agents after acute myocardial infarction (MI) is controversial. Methods We searched PubMed, Scopus, Embase, and ClinicalTrial.gov for randomized clinical trial...

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Main Authors: Davood Semirani-Nezhad, Hamidreza Soleimani, Morvarid Taebi, Khatere Roozbehi, Soodeh Jahangiri, Babak Sattartabar, Fatemeh Takaloo, Bahar parastooei, Erfan Asfa, Danyal Salabat, Mohammad Mobin Alishahi, Fatemeh Mosayebi, Yaser jenab, Rahul Gupta, Toshiki Kuno, Wilbert Aronow, Kaveh Hosseini
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cardiovascular Disorders
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Online Access:https://doi.org/10.1186/s12872-025-04992-2
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