Diffusion limitation: a possible source for the occurrence of doughnut patterns on DNA microarrays

Doughnut shaped hybridization patterns on DNA microarrays are mainly allocated to spotting or drying artifacts. The present study reports on results obtained from four different approaches that when combined generate a better view on the occurrence of these patterns. This study points out that dough...

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Bibliographic Details
Main Authors: Kris Pappaert, Heidi Ottevaere, Hugo Thienpont, Paul Van Hummelen, Gert Desmet
Format: Article
Language:English
Published: Taylor & Francis Group 2006-11-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/000112293
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