Characterization of T cells in the progression of dry eye disease using single-cell RNA sequencing in mice

Characterization of T cells in the progression of dry eye disease using single-cell RNA sequencing in mice

Abstract Background Increasing evidence indicated that T cells have significant effects in dry eye disease (DED). However, the regulatory role of T cells in DED remains unclear. Methods In this study, we examined immune responses throughout the progression in murine DED model. Using cytometry by tim...

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Bibliographic Details
Main Authors: Zhizhi Zhang, Liwei Zhang, Baihua Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:European Journal of Medical Research
Subjects:
Dry eye disease (DED)
T cell
Immune modulation
ScRNA-seq
Immune response
Therapy
Online Access:https://doi.org/10.1186/s40001-025-02607-2
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https://doi.org/10.1186/s40001-025-02607-2

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