Dual BLyS/APRIL targeted therapy with telitacicept in rituximab-refractory SLE-associated neuromyelitis optica spectrum disorder: a case report

Dual BLyS/APRIL targeted therapy with telitacicept in rituximab-refractory SLE-associated neuromyelitis optica spectrum disorder: a case report

This article presents a case of neuromyelitis optica spectrum disorder (NMOSD) secondary to systemic lupus erythematosus (SLE). The patient initially presented with unexplained nausea, vomiting, intractable hiccups, and significant bradycardia (48 bpm). Cranial and spinal MRI findings were unremarka...

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Bibliographic Details
Main Authors: Mingfen Dai, Chunyan Huang, Mingxuan Zhou, Pui-Ying Leong, Xiaoqing Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
neuromyelitis optica spectrum disorder
systemic lupus erythematosus
area postrema syndrome
optic neuritis
AQP4-IgG
telitacicept
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602800/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602800/full

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