Liraglutide improves antioxidant defense in hearts of spontaneously hypertensive female rats independently of changes in blood pressure in a pre-clinical model of menopause

Liraglutide improves antioxidant defense in hearts of spontaneously hypertensive female rats independently of changes in blood pressure in a pre-clinical model of menopause

Liraglutide (LIRA) is an agonist of the GLP-1 receptor used in the treatment of type 2 diabetes with a cardioprotective effect, although little is known about the effects of LIRA in post-menopause. We aimed to evaluate the effects of LIRA in the cardiovascular system of ovariectomized spontaneously...

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Bibliographic Details
Main Authors: W.C. dos Santos, S.N. Ronchi, L.A. Gonçalves, L.C.S.L. Oliveira, G.J. Sousa, A.F. Melo Junior, T.U. de Andrade, N.S. Bissoli, G.A. Brasil
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2025-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
GLP-1
Estrogen
Menopause
Antioxidant
Hypertension
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100634&lng=en&tlng=en
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