T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates

T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates

Backgound: Older lung transplant recipients experience increased rates of adverse clinical outcomes, including infection compared with younger patients, potentially related to impaired cell-mediated immunity, frailty, and sarcopenia. Methods: Patients over age 55 years undergoing evaluation for lung...

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Main Authors: Joanna M. Schaenman, MD, PhD, Harry Pickering, PhD, Elaine F. Reed, PhD, Maura Rossetti, PhD, Benjamin Seligman, MD, S. Samuel Weigt, MD, Michael Shino, MD, David Sayah, MD, PhD, John Belperio, MD, Ashley Hu, MD, Ashley Prosper, MD, Kathleen Ruchalski, MD, Abbas Ardehali, MD, Reshma Biniwale, MD
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JHLT Open
Subjects:
T cell
immune senescence
frailty
sarcopenia
lung transplantation
outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2950133424001496
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