Bordetella pertussis infection activates the type I interferon signaling pathway to exacerbate respiratory tract inflammatory response

The upper airway epithelium is the primary site of exposure to Bordetella pertussis and the initiator of host responses to this microbe. B. pertussis may cause serious respiratory infections resulting in major complications, as well as severe impairment of airway function. While pertussis treatment...

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Bibliographic Details
Main Authors: Wenwen Jiang, Jiangli Liang, Lukui Cai, Jingyan Li, Qin Gu, Yan Ma, Mingbo Sun, Xin-an Jiao, Li Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1521970/full
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