Metabolic syndrome, adipokines, coagulation factors, and venous thromboembolism: a two-step Mendelian randomization study

Metabolic syndrome, adipokines, coagulation factors, and venous thromboembolism: a two-step Mendelian randomization study

Abstract Objective The relationship between metabolic syndrome (MetS) and venous thromboembolism (VTE) remains controversial. To clarify this, we conducted a two-step Mendelian randomization (MR) study to elucidate these independent causal associations and to investigate the potential mediating effe...

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Bibliographic Details
Main Authors: Zhenzhen Chen, Qi Shuai, Xia Jiang, Wenci Chen, Pingping Ruan, Ruohe Li, Jing Ji, Shixuan Chen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Metabolic syndrome
Venous thromboembolism
Adipokines
Coagulation factors
Mendelian randomization
Online Access:https://doi.org/10.1186/s13098-025-01763-z
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https://doi.org/10.1186/s13098-025-01763-z

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