Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in 3xTg Alzheimer’s model mice

Abstract Executive dysfunction encompasses altered decision-making, attentional deficits, excessive risk-taking behaviours, and inefficient planning. Alongside memory loss, these cognitive deficits are amongst the most frequently reported symptoms of Alzheimer’s disease (AD). Normal executive functi...

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Bibliographic Details
Main Authors: Grace Cunliffe, Li Yang Tan, Sangyong Jung, Jonathan Turner, John Gigg
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08546-2
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