Gut microbiota-mediated bile acid transformations regulate the transport of aflatoxin B1 from the intestine to the liver in piglets

Gut microbiota-mediated bile acid transformations regulate the transport of aflatoxin B1 from the intestine to the liver in piglets

Abstract Background Aflatoxins have been reported as a significant pollutant in feed, capable of causing harm to the liver, gastrointestinal tract and kidneys of piglets. However, research on the interactions among aflatoxin B1 (AFB1), bile acid (BA) metabolism and gut microbiota is limited. Methods...

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Bibliographic Details
Main Authors: Jiangdi Mao, Yusen Wei, Zhixiang Ni, Jinzhi Zhang, Junli Zhu, Haifeng Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Aflatoxin
Bile acid
CYP8B1
FXR
Microbiota
Piglet
Online Access:https://doi.org/10.1186/s40104-025-01169-x
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https://doi.org/10.1186/s40104-025-01169-x

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