Expression quantitative trait loci influence DNA damage-induced apoptosis in cancer

Expression quantitative trait loci influence DNA damage-induced apoptosis in cancer

Abstract Background Genomic instability and evading apoptosis are two fundamental hallmarks of cancer and closely linked to DNA damage response (DDR). By analyzing expression quantitative trait loci (eQTL) upon cell stimulation (called exposure eQTL (e2QTL)) it is possible to identify context specif...

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Bibliographic Details
Main Authors: Jessica Bigge, Laura L. Koebbe, Ann-Sophie Giel, Dorothea Bornholdt, Benedikt Buerfent, Pouria Dasmeh, Alexander M. Zink, Carlo Maj, Johannes Schumacher
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Genomics
Subjects:
DNA damage
Apoptosis
Cancer
GWAS
eQTL
Online Access:https://doi.org/10.1186/s12864-024-11068-6
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https://doi.org/10.1186/s12864-024-11068-6

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