Effects of misoprostrol on pentylenetetrazol-induced seizures in mice Efeitos de misoprostrol sobre convulsões induzidas por pentilenotetrazol em camundongos
The effects of prostaglandin E - analogue misoprostol on the susceptibility to pentilenetetrazol(PTZ) - induced seizures were examined in mice. Misoprostol (200-800 mg/kg), given subcutaneously 45 min before the subconvulsive dose of PTZ (30 mg/kg, i.p) provoked dose-dependent clonic-tonic seizures...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
1997-01-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000500001 |
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