Addressing treatment switching in the ALTA-1L trial with g-methods: exploring the impact of model specification
Abstract Background Treatment switching in randomized clinical trials introduces challenges in performing causal inference. Intention To Treat (ITT) analyses often fail to fully capture the causal effect of treatment in the presence of treatment switching. Consequently, decision makers may instead b...
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| Main Authors: | Amani Al Tawil, Sean McGrath, Robin Ristl, Ulrich Mansmann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-024-02437-6 |
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