Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes

Abstract In mammals, oocytes are arrested in prophase of meiosis I for long periods of time. Prophase arrest is critical for reproduction because it allows oocytes to grow to their full size to support meiotic maturation and embryonic development. Prophase arrest requires the inhibitory phosphorylat...

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Bibliographic Details
Main Authors: Shiya Cheng, Melina Schuh
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54161-w
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