Formylation of 2-Methylpyrimidine-4,6-diol Under the Conditions of the Vilsmeier–Haack Reaction

Formylation of 2-Methylpyrimidine-4,6-diol Under the Conditions of the Vilsmeier–Haack Reaction

In the course of this work, we explored the influence of the conditions of the Vilsmeier–Haack reaction for 2-methylpyrimidine-4,6-diol (<b>1</b>). We conducted a comparative analysis of approaches using various solvents (o-xylene, N,N-dimethylformamide (DMF), benzene, and dichloroethane...

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Bibliographic Details
Main Authors: Aleksandr V. Dambaev, Denis A. Kolesnik, Igor P. Yakovlev, Tamara L. Semakova
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
formylation
pyrimidine-4,6-diols
Vilsmeier–Haack reaction
electrophilic substitution
Online Access:https://www.mdpi.com/2673-4583/16/1/104
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