p68/DdX5 supports β-catenin & RNAP II during androgen receptor mediated transcription in prostate cancer.

p68/DdX5 supports β-catenin & RNAP II during androgen receptor mediated transcription in prostate cancer.

The DEAD box RNA helicase p68 (Ddx5) is an important androgen receptor (AR) transcriptional co-activator in prostate cancer (PCa) and is over-expressed in late stage disease. β-Catenin is a multifunctional protein with important structural and signalling functions which is up-regulated in PCa and si...

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Bibliographic Details
Main Authors: Emma L Clark, Christiana Hadjimichael, Richard Temperley, Amy Barnard, Frances V Fuller-Pace, Craig N Robson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054150&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054150&type=printable

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