Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling

Abstract Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cell state. Previously, we uncovered processes in the Saccharomyces cerevisiae pheromone response system (PRS) that reduced cell‐to‐cell variability in signal strength and cellula...

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Bibliographic Details
Main Authors: C Gustavo Pesce, Stefan Zdraljevic, William J Peria, Alan Bush, María Victoria Repetto, Daniel Rockwell, Richard C Yu, Alejandro Colman‐Lerner, Roger Brent
Format: Article
Language:English
Published: Springer Nature 2018-04-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20167390
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