Inhibition of mPFC norepinephrine improved chronic post-thoracotomy pain in adult rats

Background Chronic post-thoracotomy pain (CPTP) is characterized by high incidence, long duration, and severity of pain. Medial prefrontal cortex (mPFC) is a brain region closely associated with chronic pain, and norepinephrine is involved in pain regulation. But the role of mPFC norepinephrine in C...

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Bibliographic Details
Main Authors: Fan Zhang, Weicheng Qiu, Wenxiang Qing, Jin Li, Huan Chang, Rili Yu, Yanjun Zhou, Qin Liao
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
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Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2451759
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