Evaluation of pyroptosis-associated genes in endometrial cancer utilizing a 101-combination machine learning framework and multi-omics data

Evaluation of pyroptosis-associated genes in endometrial cancer utilizing a 101-combination machine learning framework and multi-omics data

BackgroundEndometrial cancer (EC) is a common and increasingly prevalent gynecological malignancy. Pyroptosis, a pro-inflammatory form of programmed cell death, plays dual roles in cancer but remains poorly understood in the context of EC and its immune microenvironment.MethodsWe identified pyroptos...

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Bibliographic Details
Main Authors: Li Juan Huang, Chen Liu, Lin Chen, Min Tang, Shi Tong Zhan, Feng Chen, An Yi Teng, Li Na Zhou, Wei Lin Sang, Ye Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
Subjects:
endometrial cancer
pyroptosis
prognostic model
immune microenvironment
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1590405/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1590405/full

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