Targeting fibroblasts in pathological bone formation: mechanisms and treatments

Fibroblasts are integral to the pathological processes underlying abnormal bone formation, including heterotopic ossification (HO), ankylosing spondylitis (AS), and ossification of the posterior longitudinal ligament (OPLL). This review summarized the diverse roles of fibroblasts, from their transdi...

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Bibliographic Details
Main Authors: Qianyu Zhang, Qimin Song, Zeyin Li, Xinyi Wu, Yuxiong Chen, Hui Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1612950/full
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