Doxorubicin causes cognitive impairment and alters gut microbiota in both male and female juvenile rats

Abstract Many survivors of childhood cancer experience significant side effects leading to inferior quality of life like chemotherapy-induced cognitive impairment (CICI). A growing body of literature implies that the gut-brain axis modulates neurological and inflammatory physiology. Cancer therapy m...

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Bibliographic Details
Main Authors: Chadni Patel, Jeremy Willekens, Frank Diglio, Peter D. Cole
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12352-5
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