A combination of phenotypic responses and genetic adaptations enables Staphylococcus aureus to withstand inhibitory molecules secreted by Pseudomonas aeruginosa

A combination of phenotypic responses and genetic adaptations enables Staphylococcus aureus to withstand inhibitory molecules secreted by Pseudomonas aeruginosa

ABSTRACT Staphylococcus aureus and Pseudomonas aeruginosa frequently co-occur in infections, and there is evidence that their interactions can negatively affect disease outcomes. P. aeruginosa is known to be dominant, often compromising S. aureus through the secretion of inhibitory compounds. We pre...

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Bibliographic Details
Main Authors: Lukas Schwyter, Selina Niggli, Natalia Zajac, Lucy Poveda, Witold Eryk Wolski, Christian Panse, Ralph Schlapbach, Rolf Kümmerli, Jonas Grossmann
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
Subjects:
Staphylococcus aureus
Pseudomonas aeruginosa
evolutionary biology
pathogen interaction
stress adaptation
proteomics
Online Access:https://journals.asm.org/doi/10.1128/msystems.00262-25
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https://journals.asm.org/doi/10.1128/msystems.00262-25

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