Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis.

Over-representation analysis (ORA) is one of the commonest pathway analysis approaches used for the functional interpretation of metabolomics datasets. Despite the widespread use of ORA in metabolomics, the community lacks guidelines detailing its best-practice use. Many factors have a pronounced im...

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Bibliographic Details
Main Authors: Cecilia Wieder, Clément Frainay, Nathalie Poupin, Pablo Rodríguez-Mier, Florence Vinson, Juliette Cooke, Rachel Pj Lai, Jacob G Bundy, Fabien Jourdan, Timothy Ebbels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009105
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