Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury

Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury

Guillain-Barré syndrome (GBS) is a rare, frequently postinfectious neuromuscular emergency and the leading cause of acute paralytic neuropathy worldwide. GBS incidence varies considerably across geographic regions, owing predominantly to different infectious exposures. In GBS, antecedent infection l...

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Bibliographic Details
Main Author: Kenneth C. Gorson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neurology
Subjects:
Guillain-Barré syndrome
classical complement
C1q
pathophysiology
acute motor axonal neuropathy (AMAN)
acute inflammatory demyelinating polyneuropathy (AIDP)
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1572949/full
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https://www.frontiersin.org/articles/10.3389/fneur.2025.1572949/full

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