Heterogeneous tissue-specific macrophages orchestrate metastatic organotropism of breast cancer: implications for promising therapeutics

Abstract Compelling evidences have manifested that breast cancer cells prefer to metastasize to certain distant organs, including brain, lung, bone and liver. According to the canonical “seed and soil” theory, this prominent biological behavior, termed as metastatic organotropism, involves intricate...

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Bibliographic Details
Main Authors: Cenzhu Wang, Pinchao Fan, Yu Zhou, Meican Ma, Haowei Zhong, Lei Liu, Qin Chen, Kun Xu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06660-7
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