Bradykinin’s carbamylation as a mechanistic link to impaired wound healing in patients with kidney dysfunction

Bradykinin’s carbamylation as a mechanistic link to impaired wound healing in patients with kidney dysfunction

Abstract Background Uremic impairment of wound healing is a well-established phenomenon, however the etiology of this condition continues to be a medical enigma. Carbamylation, posttranslational modification (PTM) occurring with high frequency in uremic milieu, is known to have impact on structural...

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Bibliographic Details
Main Authors: Marta Kaminska, Urszula Kałucka, Janka Babickova, Małgorzata Benedyk-Machaczka, Eleni Skandalou, Melissa M. Grant, Hans-Peter Marti, Piotr Mydel
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Biology
Subjects:
Bradykinin
Wound healing
Carbamylation
Posttranslational modification
Online Access:https://doi.org/10.1186/s12915-025-02187-x
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https://doi.org/10.1186/s12915-025-02187-x

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