Comparability of a Three-Dimensional Structure in Biopharmaceuticals Using Spectroscopic Methods

Protein structure depends on weak interactions and covalent bonds, like disulfide bridges, established according to the environmental conditions. Here, we present the validation of two spectroscopic methodologies for the measurement of free and unoxidized thiols, as an attribute of structural integr...

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Bibliographic Details
Main Authors: Víctor Pérez Medina Martínez, Mario E. Abad-Javier, Alexis J. Romero-Díaz, Francisco Villaseñor-Ortega, Néstor O. Pérez, Luis F. Flores-Ortiz, Emilio Medina-Rivero
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2014/950598
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