Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue.

Early-after depolarizations (EADs) are changes in the action potential plateau that can lead to cardiac arrhythmia. At the cellular level, these oscillations are irregular and change from beat to beat due to the sensitivity of voltage repolarization to subcellular stochastic processes. However, the...

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Bibliographic Details
Main Authors: Jack Stein, D'Artagnan Greene, Flavio Fenton, Yohannes Shiferaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012635
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