A Trade‐Off Between Antimicrobial Peptide Resistance and Sensitivity to Host Immune Effectors in Staphylococcus aureus In Vivo

A Trade‐Off Between Antimicrobial Peptide Resistance and Sensitivity to Host Immune Effectors in Staphylococcus aureus In Vivo

ABSTRACT Antimicrobial peptides (AMPs) are essential immune effectors of multicellular organisms. Bacteria can evolve resistance to AMPs. Surprisingly, when used to challenge the yellow mealworm beetle, Tenebrio molitor, Staphylococcus aureus resistant to an abundant AMP (tenecin 1) of the very same...

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Bibliographic Details
Main Authors: Baydaa El Shazely, Jens Rolff
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Evolutionary Applications
Subjects:
antimicrobial peptides
antimicrobial resistance
negative pleiotropy
Tenebrio molitor
Online Access:https://doi.org/10.1111/eva.70068
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https://doi.org/10.1111/eva.70068

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