A Gram Scale Synthesis of 3,4-Dihalogen Substituted 1,8-Naphthalimides

A Gram Scale Synthesis of 3,4-Dihalogen Substituted 1,8-Naphthalimides

A general protocol for the synthesis of 3,4-dihalogen substituted 1,8-naphthalimides is proposed, starting from available and cheap 1,8-naphthalic anhydride. The reported new compounds have only bromine or chlorine atoms as substituents, in contrast to the known iodo-containing analogues. This is an...

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Bibliographic Details
Main Authors: Denitsa Anastasova, Monika Mutovska, Natali Simeonova, Irena Zagranyarska, Zlatina Vlahova, Stanimir Stoyanov, Yulian Zagranyarski
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molbank
Subjects:
1,8-naphthalic anhydride
1,8-naphthalimide
Sandmeyer reaction
bromination
chlorination
building blocks
Online Access:https://www.mdpi.com/1422-8599/2024/4/M1918
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https://www.mdpi.com/1422-8599/2024/4/M1918

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