Changes in mRNA expression of oncogenesis driver genes in atypical ductal breast hyperplasia

Changes in mRNA expression of oncogenesis driver genes in atypical ductal breast hyperplasia

Background. Atypical ductal hyperplasia is a relatively common breast lesion that increases the risk of breast cancer by 3.5 to 5 times. Genomic rearrangements underlying the development of atypical proliferative lesions and breast cancer lead to gene expression changings.Aim. To determine the mRNA...

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Bibliographic Details
Main Authors: O. V. Burmenskaya, V. V. Kometova, A. A. Smetnik, V. V. Rodionov, D. Yu. Trofimov, L. A. Ashrafyan, G. T. Sukhikh
Format: Article
Language:Russian
Published: ABV-press 2024-01-01
Series:Опухоли женской репродуктивной системы
Subjects:
atypical ductal hyperplasia of the breast
premalignant condition
breast cancer
mrna profiles of oncogenic driver genes
real-time reverse transcription polymerase chain reaction
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/1144
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