EIF2S1 in Urinary Extracellular Vesicles as a Novel Diagnostic Marker for Bladder Cancer

EIF2S1 in Urinary Extracellular Vesicles as a Novel Diagnostic Marker for Bladder Cancer

ABSTRACT Background Urinary extracellular vesicles (uEVs), directly secreted from bladder cancer (BCa) cells, harbor potential for biomarker discovery. Methods We performed proteomic analysis to explore and validate uEV‐based diagnostic markers for BCa, with a focus on cytoplasmic EV proteins. Among...

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Main Authors: Eisuke Tomiyama, Kazutoshi Fujita, Kyosuke Matsuzaki, Ryohei Narumi, Makoto Matsushita, Yujiro Hayashi, Mamoru Hashimoto, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takafumi Minami, Tetsuya Takao, Shingo Takada, Hirotsugu Uemura, Jun Adachi, Takeshi Tomonaga, Norio Nonomura
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Medicine
Subjects:
bladder cancer
cytoplasmic proteins
extracellular vesicles
liquid biopsy
proteomics
urinary markers
Online Access:https://doi.org/10.1002/cam4.70964
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https://doi.org/10.1002/cam4.70964

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