Comprehensive review of angioid streaks
Angioid streaks are irregular breaks in the brittle Bruch’s membrane and commonly present as pigmented linear lines radiating from the optic disc. They may be associated with systemic disease in up to 50% of the patients. Systemic diseases such as pseudoxanthoma elasticum, Paget’s disease, and hemog...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_812_24 |
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| author | Sindhuja Kandasamy Nawazish Shaikh Abhidnya Surve Somya Kumari Amber A. Bhayana Pradeep Kumar Rohan Chawla Vinod Kumar |
| author_facet | Sindhuja Kandasamy Nawazish Shaikh Abhidnya Surve Somya Kumari Amber A. Bhayana Pradeep Kumar Rohan Chawla Vinod Kumar |
| author_sort | Sindhuja Kandasamy |
| collection | DOAJ |
| description | Angioid streaks are irregular breaks in the brittle Bruch’s membrane and commonly present as pigmented linear lines radiating from the optic disc. They may be associated with systemic disease in up to 50% of the patients. Systemic diseases such as pseudoxanthoma elasticum, Paget’s disease, and hemoglobinopathies are commonly associated with angioid streaks. However, they may be idiopathic in a small number of cases. Patients may be asymptomatic until complications such as choroidal neovascular membrane and subretinal hemorrhage involving the fovea develop. Due to the brittle nature of Bruch’s membrane, even minor trauma could lead to subretinal hemorrhage in these eyes. Diagnosis is commonly made through clinical examination and investigations such as fundus autofluorescence and optical coherence tomography. Treatment consists of management of the choroidal neovascular membrane commonly through intravitreal antivascular endothelial growth factor injections. In this review, we provide an overview of angioid streaks right from their epidemiology to their management. |
| format | Article |
| id | doaj-art-38398403947946be8384a792ef6ba634 |
| institution | Kabale University |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-38398403947946be8384a792ef6ba6342025-01-07T06:28:38ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-01-0173Suppl 1S47S5410.4103/IJO.IJO_812_24Comprehensive review of angioid streaksSindhuja KandasamyNawazish ShaikhAbhidnya SurveSomya KumariAmber A. BhayanaPradeep KumarRohan ChawlaVinod KumarAngioid streaks are irregular breaks in the brittle Bruch’s membrane and commonly present as pigmented linear lines radiating from the optic disc. They may be associated with systemic disease in up to 50% of the patients. Systemic diseases such as pseudoxanthoma elasticum, Paget’s disease, and hemoglobinopathies are commonly associated with angioid streaks. However, they may be idiopathic in a small number of cases. Patients may be asymptomatic until complications such as choroidal neovascular membrane and subretinal hemorrhage involving the fovea develop. Due to the brittle nature of Bruch’s membrane, even minor trauma could lead to subretinal hemorrhage in these eyes. Diagnosis is commonly made through clinical examination and investigations such as fundus autofluorescence and optical coherence tomography. Treatment consists of management of the choroidal neovascular membrane commonly through intravitreal antivascular endothelial growth factor injections. In this review, we provide an overview of angioid streaks right from their epidemiology to their management.https://journals.lww.com/10.4103/IJO.IJO_812_24angioid streakshemoglobinopathiespaget’s diseasepseudoxanthoma elasticum |
| spellingShingle | Sindhuja Kandasamy Nawazish Shaikh Abhidnya Surve Somya Kumari Amber A. Bhayana Pradeep Kumar Rohan Chawla Vinod Kumar Comprehensive review of angioid streaks Indian Journal of Ophthalmology angioid streaks hemoglobinopathies paget’s disease pseudoxanthoma elasticum |
| title | Comprehensive review of angioid streaks |
| title_full | Comprehensive review of angioid streaks |
| title_fullStr | Comprehensive review of angioid streaks |
| title_full_unstemmed | Comprehensive review of angioid streaks |
| title_short | Comprehensive review of angioid streaks |
| title_sort | comprehensive review of angioid streaks |
| topic | angioid streaks hemoglobinopathies paget’s disease pseudoxanthoma elasticum |
| url | https://journals.lww.com/10.4103/IJO.IJO_812_24 |
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