Efficacy of cholinesterase inhibitors and memantine on symptoms not responsive to levodopa in patients affected by Parkinson’s disease without dementia: a systematic review

Efficacy of cholinesterase inhibitors and memantine on symptoms not responsive to levodopa in patients affected by Parkinson’s disease without dementia: a systematic review

Background Parkinson’s disease (PD) is primarily characterised by parkinsonism due to nigro-striatal dopaminergic denervation. While therapeutic strategies have traditionally focused on compensating for dopaminergic deficit, growing evidence reveals an involvement of cholinergic and glutamatergic pa...

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Main Authors: Pietro Cortelli, Maria Guarino, Giovanna Calandra-Buonaura, Giulia Giannini, Pietro Guaraldi, Francesco Nonino, Ilaria Cani, Nicola Grotteschi, Luca Baldelli, Monia Donati, Maria Domenica Camerlingo, Luisa Sambati
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:BMJ Neurology Open
Online Access:https://neurologyopen.bmj.com/content/7/2/e001079.full
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https://neurologyopen.bmj.com/content/7/2/e001079.full

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