Oxaliplatin Analogues with Carboxy Derivatives of Boldine with Enhanced Antioxidant Activity

A new oxaliplatin analog [Pt(dach)(L5)] (1) was synthesized and characterized as a continuation of a study of the previously reported [Pt(dach)(L6)] (2), where dach = (1R,2R)-diaminocyclohexane, L5 = 3-carboxyboldine, and L6 = 3-carboxypredicentrine. Compounds 1 and 2 exhibited a substantially enhan...

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Bibliographic Details
Main Authors: Marco Mellado, Carlos Jara, David Astudillo, Joan Villena, Patricio G. Reveco, Franz A. Thomet
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2015/920143
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