Mitochondria dysfunction, a potential cytoprotection target against ischemia-reperfusion injury in a mouse stroke model

Mitochondria dysfunction, a potential cytoprotection target against ischemia-reperfusion injury in a mouse stroke model

More than 50 ​% of patients undergoing mechanical thrombectomy (MT) for ischemic stroke have a poor functional outcome despite timely and successful angiographic reperfusion, highlighting the need for adjunctive treatments to reperfusion therapy. Mitochondria are key regulators of cell fate, by cont...

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Bibliographic Details
Main Authors: Elodie Ong, Paul Clottes, Christelle Leon, Hala Guedouari, Noelle Gallo-Bona, Megane Lo Grasso, Lucas Motter, Radu Bolbos, Michel Ovize, Norbert Nighogossian, Marlene Wiart, Melanie Paillard
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neurotherapeutics
Subjects:
Cerebral ischemia-reperfusion
PTP
Mitochondrial respiration
Therapeutic
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747925000273
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