Vitreous Diagnosis in Neoplastic Diseases

Vitreous body is an intraocular structure, origin of diverse pathologies, but is also the place where cells and inflammatory mediators are released coming from several pathologic processes. These inflammatory reactions can happen in any other ocular location like choroid, retina, optic nerve, or cil...

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Main Authors: Mónica Asencio-Duran, José Luis Vallejo-Garcia, Natalia Pastora-Salvador, Agustín Fonseca-Sandomingo, Mario R. Romano
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/930704
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author Mónica Asencio-Duran
José Luis Vallejo-Garcia
Natalia Pastora-Salvador
Agustín Fonseca-Sandomingo
Mario R. Romano
author_facet Mónica Asencio-Duran
José Luis Vallejo-Garcia
Natalia Pastora-Salvador
Agustín Fonseca-Sandomingo
Mario R. Romano
author_sort Mónica Asencio-Duran
collection DOAJ
description Vitreous body is an intraocular structure, origin of diverse pathologies, but is also the place where cells and inflammatory mediators are released coming from several pathologic processes. These inflammatory reactions can happen in any other ocular location like choroid, retina, optic nerve, or ciliary body and vitreous humor constitutes a stagnant reservoir for these resulting substances and debris. Through the recent techniques of vitreous collecting, handling, and analysis, increasingly more sophisticated and with fewer complications, cellularity and molecules in the vitreous of challenging pathologies for the ophthalmologist can now be studied. The most usefulness for vitreous diagnosis would be the masquerade syndromes, and the best exponent in this group is the primary vitreoretinal lymphoma (PVRL), in which cytology and an IL-10/IL-6 ratio more than 1 is fundamental for the diagnosis.
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institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-37db37298c8e48f589bf09ca76b3394c2025-02-03T01:09:51ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/930704930704Vitreous Diagnosis in Neoplastic DiseasesMónica Asencio-Duran0José Luis Vallejo-Garcia1Natalia Pastora-Salvador2Agustín Fonseca-Sandomingo3Mario R. Romano4Hospital La Paz, Madrid, SpainIstituto Clinico Humanitas, Milano, ItalyHospital La Paz, Madrid, SpainHospital La Paz, Madrid, SpainIstituto Clinico Humanitas, Milano, ItalyVitreous body is an intraocular structure, origin of diverse pathologies, but is also the place where cells and inflammatory mediators are released coming from several pathologic processes. These inflammatory reactions can happen in any other ocular location like choroid, retina, optic nerve, or ciliary body and vitreous humor constitutes a stagnant reservoir for these resulting substances and debris. Through the recent techniques of vitreous collecting, handling, and analysis, increasingly more sophisticated and with fewer complications, cellularity and molecules in the vitreous of challenging pathologies for the ophthalmologist can now be studied. The most usefulness for vitreous diagnosis would be the masquerade syndromes, and the best exponent in this group is the primary vitreoretinal lymphoma (PVRL), in which cytology and an IL-10/IL-6 ratio more than 1 is fundamental for the diagnosis.http://dx.doi.org/10.1155/2012/930704
spellingShingle Mónica Asencio-Duran
José Luis Vallejo-Garcia
Natalia Pastora-Salvador
Agustín Fonseca-Sandomingo
Mario R. Romano
Vitreous Diagnosis in Neoplastic Diseases
Mediators of Inflammation
title Vitreous Diagnosis in Neoplastic Diseases
title_full Vitreous Diagnosis in Neoplastic Diseases
title_fullStr Vitreous Diagnosis in Neoplastic Diseases
title_full_unstemmed Vitreous Diagnosis in Neoplastic Diseases
title_short Vitreous Diagnosis in Neoplastic Diseases
title_sort vitreous diagnosis in neoplastic diseases
url http://dx.doi.org/10.1155/2012/930704
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AT joseluisvallejogarcia vitreousdiagnosisinneoplasticdiseases
AT nataliapastorasalvador vitreousdiagnosisinneoplasticdiseases
AT agustinfonsecasandomingo vitreousdiagnosisinneoplasticdiseases
AT mariorromano vitreousdiagnosisinneoplasticdiseases