Kidney cancer PDOXs reveal patient‐specific pro‐malignant effects of antiangiogenics and its molecular traits

Kidney cancer PDOXs reveal patient‐specific pro‐malignant effects of antiangiogenics and its molecular traits

Abstract An open debate in antiangiogenic therapies is about their consequence on tumor invasiveness and metastasis, which is undoubtedly relevant for patients currently treated with antiangiogenics, such as renal cell carcinoma patients. To address, this we developed an extensive series of 27 patie...

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Main Authors: Lidia Moserle, Roser Pons, Mar Martínez‐Lozano, Gabriela A Jiménez‐Valerio, August Vidal, Cristina Suárez, Enrique Trilla, José Jiménez, Inés de Torres, Joan Carles, Jordi Senserrich, Susana Aguilar, Luis Palomero, Alberto Amadori, Oriol Casanovas
Format: Article
Language:English
Published: Springer Nature 2020-11-01
Series:EMBO Molecular Medicine
Subjects:
antiangiogenics
biomarker
cancer resistance
metastasis induction
orthotopic models of kidney cancer
Online Access:https://doi.org/10.15252/emmm.201911889
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https://doi.org/10.15252/emmm.201911889

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