Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure
Rapid respiratory failure due to invasive mycosis of the airways is an uncommon presentation of Aspergillus infection, even in immunocompromised patients, and very few pediatric cases have been reported. Patients with Aspergillus tracheobronchitis present with nonspecific symptoms, and radiologic st...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2016/9676234 |
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| author | Stefanie Gauguet Kate Madden Jennifer Wu Christine Duncan Gi Soo Lee Tonya Miller William C. Klingensmith Sandra K. Burchett Meredith van der Velden |
| author_facet | Stefanie Gauguet Kate Madden Jennifer Wu Christine Duncan Gi Soo Lee Tonya Miller William C. Klingensmith Sandra K. Burchett Meredith van der Velden |
| author_sort | Stefanie Gauguet |
| collection | DOAJ |
| description | Rapid respiratory failure due to invasive mycosis of the airways is an uncommon presentation of Aspergillus infection, even in immunocompromised patients, and very few pediatric cases have been reported. Patients with Aspergillus tracheobronchitis present with nonspecific symptoms, and radiologic studies are often noninformative, leading to a delay in diagnosis. Prompt initiation of adequate antifungal therapies is of utmost importance to improve outcome. We report the case of a 9-year-old girl with chronic myelogenous leukemia who developed respiratory distress 41 days after hematopoietic cell transplantation and rapidly deteriorated despite multiple interventions and treatment modalities. |
| format | Article |
| id | doaj-art-37c22086e17f4eb19c6d5855553ee886 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-37c22086e17f4eb19c6d5855553ee8862025-02-03T01:30:58ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/96762349676234Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory FailureStefanie Gauguet0Kate Madden1Jennifer Wu2Christine Duncan3Gi Soo Lee4Tonya Miller5William C. Klingensmith6Sandra K. Burchett7Meredith van der Velden8Division of Pediatric Critical Care, Department of Pediatrics, UMass Memorial Children’s Medical Center, University of Massachusetts Medical School, 55 North Lake Avenue, Worcester, MA 01655, USADivision of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADivision of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADivision of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADepartment of Otolaryngology and Communication Enhancement, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADivision of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADepartment of Pathology, Midland Memorial Hospital, Midland, TX 79701, USADivision of Infectious Diseases, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USADivision of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USARapid respiratory failure due to invasive mycosis of the airways is an uncommon presentation of Aspergillus infection, even in immunocompromised patients, and very few pediatric cases have been reported. Patients with Aspergillus tracheobronchitis present with nonspecific symptoms, and radiologic studies are often noninformative, leading to a delay in diagnosis. Prompt initiation of adequate antifungal therapies is of utmost importance to improve outcome. We report the case of a 9-year-old girl with chronic myelogenous leukemia who developed respiratory distress 41 days after hematopoietic cell transplantation and rapidly deteriorated despite multiple interventions and treatment modalities.http://dx.doi.org/10.1155/2016/9676234 |
| spellingShingle | Stefanie Gauguet Kate Madden Jennifer Wu Christine Duncan Gi Soo Lee Tonya Miller William C. Klingensmith Sandra K. Burchett Meredith van der Velden Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure Case Reports in Pediatrics |
| title | Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure |
| title_full | Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure |
| title_fullStr | Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure |
| title_full_unstemmed | Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure |
| title_short | Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure |
| title_sort | case report of a child after hematopoietic cell transplantation with acute aspergillus tracheobronchitis as a cause for respiratory failure |
| url | http://dx.doi.org/10.1155/2016/9676234 |
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