Mitochondrial DNA and Functional Investigations into the Radiosensitivity of Four Mouse Strains

Mitochondrial DNA and Functional Investigations into the Radiosensitivity of Four Mouse Strains

We investigated whether genetic radiosensitivity-related changes in mtDNA/nDNA ratios are significant to mitochondrial function and if a material effect on mtDNA content and function exists. BALB/c (radiosensitive), C57BL/6 (radioresistant), and F1 hybrid mouse strains were exposed to total body irr...

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Main Authors: Steven B. Zhang, David Maguire, Mei Zhang, Yeping Tian, Shanmin Yang, Amy Zhang, Katherine Casey-Sawicki, Deping Han, Jun Ma, Liangjie Yin, Yongson Guo, Xiaohui Wang, Chun Chen, Alexandra Litvinchuk, Zhenhuan Zhang, Steven Swarts, Sadasivan Vidyasagar, Lurong Zhang, Paul Okunieff
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2014/850460
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http://dx.doi.org/10.1155/2014/850460

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