ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets

Abstract Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) enables paired measurement of surface protein and mRNA expression in single cells using antibodies conjugated to oligonucleotide tags. Due to the high copy number of surface protein molecules, sequencing antibody-deri...

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Main Authors: Ye Zheng, Daniel P. Caron, Ju Yeong Kim, Seong-Hwan Jun, Yuan Tian, Florian Mair, Kenneth D. Stuart, Peter A. Sims, Raphael Gottardo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61023-6
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https://doi.org/10.1038/s41467-025-61023-6

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